Journal: Scientific Reports
Article Title: Diffuse reflectance spectroscopy and imaging for non-invasive objective assessment of genitourinary syndrome of menopause: a pilot study
doi: 10.1038/s41598-023-49655-4
Figure Lengend Snippet: Diffuse reflectance spectroscopy and imaging (DRSI) system. ( a ) Illustration of probe parameters and detection depth in the vulvar skin (E: epidermis, D: dermis, H: hypodermis) in the transverse view. ( b ) Schematic of the investigated vulva locations marked from 1 to 9 which display GSM symptoms. ( c ) Raw spectrum of the average of all locations for all premenopausal (solid line), perimenopausal (dashed line), and postmenopausal (dotted line) subjects.
Article Snippet: The raw spectra S( λ i ) collected for each location were divided by the white reflectance (5′′ Spectralon ® Diffuse Reflectance Target, Edmund Optics) reference spectrum W( λ i ) to obtain the normalised intensity spectra R( λ i ) after subtracting the background spectrum B( λ i ) from both as represented in Eq. ( ) .
Techniques: Spectroscopy, Imaging